Mazhar Kaleem was born on 22 July 1942 in Multan.He belongs to a Pathan family,"Muhammad Zai" in Multan. Mazhar Kaleem is a Pakistani novelist chiefly famous for his Imran Series novels, Urdu spy fiction. written with in Imran Series mythos created by the late Ibn-e-Safi.
He is known for writing the Imran Series and has written short stories for children as well. He is the anchorperson of a famous saraiki radio talk show from Radio Multan, "Jamhoor-de-Awaz". He is a successful lawyer who was elected as Senior Vice President of Multan Bar Council and he heads a chamber in District Courts Multan.